5-Formyl-2'-deoxyuridine
5-Formyl-2'-deoxyuridine is a product formed when the 5-methyl group of thymine in DNA undergoes oxidation due to exposure to gamma radiation or certain chemical agents. Serving as a biomarker of oxidative DNA damage, 5-formyl-2'-deoxyuridine is employed in investigations of DNA damage and repair mechanisms. Additionally, 5-Formyl-2'-deoxyuridine can be used in studies involving chemically crosslinking with peptides derived from the RecA protein[1].
Product Specifications
CAS Number
4494-26-2
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
Endogenous Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/5-formyl-2-deoxyuridine.html
Purity
99.64
Solubility
DMSO : 200 mg/mL (ultrasonic)
Smiles
OC[C@@H]1[C@@H](O)C[C@H](N2C=C(C=O)C(NC2=O)=O)O1
Molecular Formula
C10H12N2O6
Molecular Weight
256.21
Precautions
H315, H319, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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