MP07-66
MP07-66, a FTY720 analogue, is devoid of immunosuppressive effects and shows promising antitumor effects in chronic lymphocytic leukemia by disruption of the SET-PP2A complex leading to PP2A reactivation[1].
Product Specifications
CAS Number
[1938056-90-6]
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
Phosphatase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mp07-66.html
Purity
99.86
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
CCCCCCOC1=CC=C(CNCC(OCC)OCC)C=C1
Molecular Formula
C19H33NO3
Molecular Weight
323.47
Precautions
H315, H319, H335
References & Citations
[1]Zonta F, et al. Lyn sustains oncogenic signaling in chronic lymphocytic leukemia by strengthening SET-mediated inhibition of PP2A. Blood. 2015;125 (24) :3747-3755.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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