Procyanidol B4 (Standard)

Procyanidol B4 (Standard) is the analytical standard of Procyanidol B4 (HY-107208) . This product is intended for research and analytical applications. Procyanidol B4 ((-) -Procyanidin B4) is an orally active polyphenol found in Q.gilva. Procyanidol B4 exerts antioxidant activity by scavenging DPPH (HY-112053) (IC50: 12.15 μM) and Nitro blue tetrazolium chloride (NBT) (HY-15925) (IC50: 8.67 μM) . Procyanidol B4 exhibits anti-inflammatory activity by inhibiting the expression of COX-2 and IL-1β and iNOS [1][2].

Product Specifications

CAS Number

[29106-51-2]

Product Name Alternative

(-) -Procyanidin B4 (Standard)

UNSPSC

12352005

Target

COX; Interleukin Related; NO Synthase; Reactive Oxygen Species (ROS) ; Reference Standards

Type

Reference compound

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; Others

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/procyanidol-b4-standard.html

Smiles

O[C@H]1[C@H](C2=C3C(C[C@@H](O)[C@@H](C4=CC(O)=C(O)C=C4)O3)=C(O)C=C2O)C5=C(O)C=C(O)C=C5O[C@@H]1C6=CC(O)=C(O)C=C6

Molecular Formula

C30H26O12

Molecular Weight

578.52

References & Citations

[1]Katoh, M., et al. Synthesis of Procyanidin B1, B2, and B4 and Their Anti-Inflammatory Activity: The Effect of 4-Alkoxy Group of Catechin and/or Epicatechin Electrophiles for Condensation.