Complement Factor B/CFB Protein, Mouse (His)

CFB is an important component of the alternative pathway of the complement system and is cleaved by factor D, producing two fragments: Ba and Bb. The Bb fragment is characterized as a serine protease and subsequently forms a complex with complement factor 3b, ultimately producing a C3 or C5 convertase. Complement Factor B/CFB Protein, Mouse (His) is the recombinant mouse-derived CFB protein, expressed by E. coli , with N-6*His labeled tag. The total length of Complement Factor B/CFB Protein, Mouse (His) is 739 a.a., with molecular weight of ~87 kDa.

TPVLEARPQV SCSLEGVEIK GGSFQLLQGG QALEYLCPSG FYPYPVQTRT CRSTGSWSDL QTRDQKIVQK AECRAIRCPR PQDFENGEFW PRSPFYNLSD QISFQCYDGY VLRGSANRTC QENGRWDGQT AICDDGAGYC PNPGIPIGTR KVGSQYRLED IVTYHCSRGL VLRGSQKRKC QEGGSWSGTE PSCQDSFMYD SPQEVAEAFL SSLTETIEGA DAEDGHSPGE QQKRKIVLDP SGSMNIYLVL DGSDSIGSSN FTGAKRCLTN LIEKVASYGV RPRYGLLTYA TVPKVLVRVS DERSSDADWV TEKLNQISYE DHKLKSGTNT KRALQAVYSM MSWAGDAPPE GWNRTRHVII IMTDGLHNMG GNPVTVIQDI RALLDIGRDP KNPREDYLDV YVFGVGPLVD SVNINALASK KDNEHHVFKV KDMEDLENVF YQMIDETKSL SLCGMVWEHK KGNDYHKQPW QAKISVTRPL KGHETCMGAV VSEYFVLTAA HCFMVDDQKH SIKVSVGGQR RDLEIEEVLF HPKYNINGKK AEGIPEFYDY DVALVKLKNK LKYGQTLRPI CLPCTEGTTR ALRLPQTATC KQHKEQLLPV KDVKALFVSE QGKSLTRKEV YIKNGDKKAS CERDATKAQG YEKVKDASEV VTPRFLCTGG VDPYADPNTC KGDSGGPLIV HKRSRFIQVG VISWGVVDVC RDQRRQQLVP SYARDFHINL FQVLPWLKDK LKDEDLGFL