Clanfenur
Clanfenur is a substituted benzoylphenylurea, an analogue of the pesticide fenfluramide, with potential antineoplastic activity. Clanfenur can bind to the colchicine-binding site on β-tubulin, inhibit microtubule polymerization, and thus prevent tumor cell replication[1].
Product Specifications
CAS Number
51213-99-1
UNSPSC
12352005
Hazard Statement
H315, H319
Target
Microtubule/Tubulin
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/clanfenur.html
Purity
99.53
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
ClC(C=C1)=CC=C1NC(NC(C2=C(C=CC=C2F)N(C)C)=O)=O
Molecular Formula
C16H15ClFN3O2
Molecular Weight
335.77
Precautions
H315, H319
References & Citations
[1]J D Jonkman-de Vries, et al. Pharmaceutical development of a parenteral formulation of the investigational anticancer drug clanfenur. PDA J Pharm Sci Technol. 1997 Mar-Apr;51 (2) :89-95.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
TP720141L 500 µg
Protein phosphatase inhibitor 1 (PPP1R1A) (NM_006741) Human Recombinant Protein
Sign In for Pricing
View Details 
F-7201-1 1 mg
FITC Conjugated Cancer antennarius Lectin (California crab) -CCA-
Sign In for Pricing
View Details 