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Fipronil sulfone

Fipronil sulfone is the major metabolite of Fipronil.Fipronil sulfone selectively inhibits GABA receptor with IC50 of 175 nM (assayed by displacement of 4′-ethynyl-4-n-[2,3-3H2]- propylbicycloorthobenzoate ([3H]EBOB) from the noncompetitive blocker site) .

Product Specifications

CAS Number

[120068-36-2]

UNSPSC

12352005

Hazard Statement

H301, H410

Target

GABA Receptor

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/fipronil-sulfone.html

Purity

99.75

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

N#CC1=NN(C(N)=C1S(=O)(C(F)(F)F)=O)C2=C(C=C(C=C2Cl)C(F)(F)F)Cl

Molecular Formula

C12H4Cl2F6N4O2S

Molecular Weight

453.15

Precautions

H301, H410

References & Citations

[1]D Hainzl, et al. Mechanisms for selective toxicity of fipronil insecticide and its sulfone metabolite and desulfinyl photoproduct. Chem Res Toxicol . 1998 Dec;11 (12) :1529-35.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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