Fipronil sulfone
Fipronil sulfone is the major metabolite of Fipronil.Fipronil sulfone selectively inhibits GABA receptor with IC50 of 175 nM (assayed by displacement of 4′-ethynyl-4-n-[2,3-3H2]- propylbicycloorthobenzoate ([3H]EBOB) from the noncompetitive blocker site) .
Product Specifications
CAS Number
120068-36-2
UNSPSC
12352005
Hazard Statement
H301, H410
Target
GABA Receptor
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/fipronil-sulfone.html
Purity
99.75
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
N#CC1=NN(C(N)=C1S(=O)(C(F)(F)F)=O)C2=C(C=C(C=C2Cl)C(F)(F)F)Cl
Molecular Formula
C12H4Cl2F6N4O2S
Molecular Weight
453.15
Precautions
H301, H410
References & Citations
[1]D Hainzl, et al. Mechanisms for selective toxicity of fipronil insecticide and its sulfone metabolite and desulfinyl photoproduct. Chem Res Toxicol . 1998 Dec;11 (12) :1529-35.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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