SIAH1 Recombinant Rabbit Monoclonal Antibody [PSH0-46]

E3 ubiquitin-protein ligase SIAH1 is an enzyme that in humans is encoded by the SIAH1 gene. This gene encodes for a polypeptide structure that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in the development of certain forms of Parkinson's disease, the regulation of the cellular response to hypoxia and induction of apoptosis. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized.

Product Specifications

CAS Number

9000-83-3

Product Name Alternative

E3 ubiquitin-protein ligase SIAH1 antibody FLJ08065 antibody hSIAH1 antibody HUMSIAH antibody Seven in absentia homolog 1 (Drosophila) antibody Seven in absentia homolog 1 antibody Siah 1 antibody Siah 1a antibody Siah E3 ubiquitin protein ligase 1 antibody Siah-1 antibody Siah-1a antibody Siah1 antibody SIAH1_HUMAN antibody SIAH1A antibody Ubiquitin ligase SIAH1 antibody

Abbreviation

SIAH1, HUMSIAH

Swiss Prot

Q8IUQ4 Human, P61092 Mouse, Q920M9 Rat

Cellular Locus

Cytoplasm, Nucleus.

Host

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Synthetic peptide within human SIAH1 aa 1-50 / 282.

Isotype

IgG

Clone

PSH0-46

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IHC-P, IF-Cell, FC

Positive Control

Jurkat cell lysate, HeLa cell lysate, HepG2 cell lysate, A549 cell lysate, human brain tissue, human testis tissue, mouse brain tissue, mouse testis tissue, rat brain tissue, rat testis tissue, A549.