Kp7-6
Kp7-6, a Fas mimetic peptide, is a Fas/FasL antagonist. Kp7-6 protects cells from Fas-mediated apoptosis, and protects mice from Fas-mediated hepatic injury[1][2].
Product Specifications
UNSPSC
12352209
Target
Apoptosis
Type
Peptides
Related Pathways
Apoptosis
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Cancer; Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/kp7-6.html
Purity
99.28
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(N[C@H](C(N[C@@H](CSSC[C@@H](C(N[C@H](C(N[C@H](C(N1)=O)CCC(O)=O)=O)CC(O)=O)=O)NC([C@@H](N)CC2=CC=C(C=C2)O)=O)C(N[C@H](C(O)=O)CC3=CC=C(C=C3)O)=O)=O)CC4=CC=CC=C4)[C@@H]1CC5=CN=CN5
Molecular Formula
C48H56N10O15S2
Molecular Weight
1077.15
References & Citations
[1]Zhang S, et al. Fas-associated death receptor signaling evoked by human amylin in islet beta-cells. Diabetes. 2008 Feb;57 (2) :348-56.|[2]Hasegawa A, et al. Fas-disabling small exocyclic peptide mimetics limit apoptosis by an unexpected mechanism. Proc Natl Acad Sci U S A. 2004 Apr 27;101 (17) :6599-604.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-P10102/Kp7-6-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-P10102/Kp7-6-SDS-MedChemExpress.pdf
Scientific Category
Peptides
Clinical Information
No Development Reported
CAS Number
[629628-53-1]
Available Sizes
Curated Selection
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