Kp7-6

Kp7-6, a Fas mimetic peptide, is a Fas/FasL antagonist. Kp7-6 protects cells from Fas-mediated apoptosis, and protects mice from Fas-mediated hepatic injury[1][2].

Product Specifications

CAS Number

[629628-53-1]

UNSPSC

12352209

Target

Apoptosis

Type

Peptides

Related Pathways

Apoptosis

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Cancer; Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/kp7-6.html

Purity

99.28

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(N[C@H](C(N[C@@H](CSSC[C@@H](C(N[C@H](C(N[C@H](C(N1)=O)CCC(O)=O)=O)CC(O)=O)=O)NC([C@@H](N)CC2=CC=C(C=C2)O)=O)C(N[C@H](C(O)=O)CC3=CC=C(C=C3)O)=O)=O)CC4=CC=CC=C4)[C@@H]1CC5=CN=CN5

Molecular Formula

C48H56N10O15S2

Molecular Weight

1077.15

References & Citations

[1]Zhang S, et al. Fas-associated death receptor signaling evoked by human amylin in islet beta-cells. Diabetes. 2008 Feb;57 (2) :348-56.|[2]Hasegawa A, et al. Fas-disabling small exocyclic peptide mimetics limit apoptosis by an unexpected mechanism. Proc Natl Acad Sci U S A. 2004 Apr 27;101 (17) :6599-604.