BACE2-IN-1
Product Specifications
UNSPSC Description
BACE2-IN-1 (compound 3l) is a highly selective BACE2 inhibitor with a Ki value of 1.6 nM. BACE2 inhibitors can be used to research of Type 2 Diabetes[1].
Target Antigen
Beta-secretase
Type
Reference compound
Related Pathways
Neuronal Signaling
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/bace2-in-1.html
Smiles
O=C(C1=CC(C)=CC(C(N[C@@H](CC2=CC=CC=C2)[C@H](O)CNCC3=CC=CC(C(F)(F)F)=C3)=O)=C1)N(C)[C@@H](C4=CC=CC=C4)C
Molecular Weight
617.70
References & Citations
[1]Ghosh AK, et al. Highly Selective and Potent Human β-Secretase 2 (BACE2) Inhibitors against Type 2 Diabetes: Design, Synthesis, X-ray Structure and Structure-Activity Relationship Studies. ChemMedChem. 2019 Mar 5. 14(5):545-560.
Shipping Conditions
Blue Ice
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-136742/BACE2-IN-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-136742/BACE2-IN-1-SDS-MedChemExpress.pdf
CAS Number
1676107-08-6
Available Sizes
Curated Selection
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