PRI2 rabbit pAb
This gene encodes the 58 kilodalton subunit of DNA primase, an enzyme that plays a key role in the replication of DNA. The encoded protein forms a heterodimer with a 49 kilodalton subunit. This heterodimer functions as a DNA-directed RNA polymerase to synthesize small RNA primers that are used to create Okazaki fragments on the lagging strand of the DNA. Alternative splicing of this gene results in multiple transcript variants. This gene has a related pseudogene, which is also present on chromosome 6. [provided by RefSeq, Apr 2014],
Product Specifications
Background
UniProt
P49643
Swiss Prot
P49643
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized peptide derived from human PRI2 AA range: 369-419
Target
PRI2
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC
Concentration
1 mg/ml
Dilution
WB 1:500-2000; IHC-p 1:50-300
Buffer
-20°C/1 year
Storage Conditions
-20°C/1 year
Fragment
IgG
Subcellular Location
Nucleoplasm, alpha DNA polymerase:primase complex, primosome complex
Gene ID (Human)
5558
Available Sizes
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