Butoconazole (nitrate)
Butoconazole nitrate (RS 35887), an imidazole antifungal agent, is active against Candida spp. and effective against vaginal infections due to Candida albicans. Butoconazole nitrate is presumed to function as other imidazole derivatives via inhibition of steroid synthesis[1][2].
Product Specifications
CAS Number
64872-77-1
Product Name Alternative
RS 35887
UNSPSC
12352005
Hazard Statement
H302
Target
Fungal
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/Butoconazole-nitrate.html
Purity
99.87
Solubility
DMSO : ≥ 100 mg/mL|H2O : < 0.1 mg/mL
Smiles
ClC1=C(SC(CCC2=CC=C(Cl)C=C2)CN3C=CN=C3)C(Cl)=CC=C1.O[N+]([O-])=O
Molecular Formula
C19H18Cl3N3O3S
Molecular Weight
474.79
Precautions
H302
References & Citations
[1]Anik ST, et al. Extreme vertexes design in formulation development: solubility of butoconazole nitrate in a multicomponent system. J Pharm Sci. 1981;70 (8) :897-900.|[2]Pharmacology refers to the chemical makeup and behavior of GYNAZOLE 1 (butoconazole nitrate cream) .
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
Launched
Available Sizes
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