Butoconazole (nitrate)

Butoconazole nitrate (RS 35887), an imidazole antifungal agent, is active against Candida spp. and effective against vaginal infections due to Candida albicans. Butoconazole nitrate is presumed to function as other imidazole derivatives via inhibition of steroid synthesis[1][2].

Product Specifications

CAS Number

[64872-77-1]

Product Name Alternative

RS 35887

UNSPSC

12352005

Hazard Statement

H302

Target

Fungal

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/Butoconazole-nitrate.html

Purity

99.87

Solubility

DMSO : ≥ 100 mg/mL|H2O : < 0.1 mg/mL

Smiles

ClC1=C(SC(CCC2=CC=C(Cl)C=C2)CN3C=CN=C3)C(Cl)=CC=C1.O[N+]([O-])=O

Molecular Formula

C19H18Cl3N3O3S

Molecular Weight

474.79

Precautions

H302

References & Citations

[1]Anik ST, et al. Extreme vertexes design in formulation development: solubility of butoconazole nitrate in a multicomponent system. J Pharm Sci. 1981;70 (8) :897-900.|[2]Pharmacology refers to the chemical makeup and behavior of GYNAZOLE 1 (butoconazole nitrate cream) .