Felcisetrag
Felcisetrag (TD-8954) is an orally active, potent and selective 5-HT4 receptor agonist with gastrointestinal prokinetic properties. Felcisetrag has high affinity (pKi =9.4) for human 5-HT4 (c) receptors.
Product Specifications
CAS Number
[916075-84-8]
Product Name Alternative
TD-8954
UNSPSC
12352005
Target
5-HT Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/felcisetrag.html
Concentration
10mM
Purity
99.94
Solubility
DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(N1CCC(CN2CCC(CNC(C3=C4C(N=C(C(C)C)N4)=CC=C3)=O)CC2)CC1)OC
Molecular Formula
C25H37N5O3
Molecular Weight
455.59
References & Citations
[1]Beattie DT, et al. The Pharmacology of TD-8954, a Potent and Selective 5-HT (4) Receptor Agonist with Gastrointestinal Prokinetic Properties. Front Pharmacol. 2011;2:25.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Isoform
Apolipoprotein D
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