Felcisetrag

Felcisetrag (TD-8954) is an orally active, potent and selective 5-HT4 receptor agonist with gastrointestinal prokinetic properties. Felcisetrag has high affinity (pKi =9.4) for human 5-HT4 (c) receptors.

Product Specifications

CAS Number

[916075-84-8]

Product Name Alternative

TD-8954

UNSPSC

12352005

Target

5-HT Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/felcisetrag.html

Concentration

10mM

Purity

99.94

Solubility

DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C(N1CCC(CN2CCC(CNC(C3=C4C(N=C(C(C)C)N4)=CC=C3)=O)CC2)CC1)OC

Molecular Formula

C25H37N5O3

Molecular Weight

455.59

References & Citations

[1]Beattie DT, et al. The Pharmacology of TD-8954, a Potent and Selective 5-HT (4) Receptor Agonist with Gastrointestinal Prokinetic Properties. Front Pharmacol. 2011;2:25.