Human CD32b (Luc) Jurkat Reporter Cell

Human CD32b (Luc) Jurkat Reporter Cell is expressed from Human Jurkat.

Product Specifications

Background

Fcγ receptors (FcγRs), the largest group of FcRs, bind IgG and comprise several subtypes. Low- affinity FcγRs, including two activating receptors (FcγRIIIa (CD16A) and FcγRIIa (CD32A) ) and a inhibitory receptor (FcγRIIb (CD32B) ), are important mediators of antibody functions in vivo, including antibody-dependent cellular cytotoxicity (ADCC), antibody-dependent cellular phagocytosis (ADCP), and induction of cytokines and chemokines. The inhibitory receptor, FcγRIIb (CD32B), contains an immunoreceptor tyrosine-based inhibition motif that counters cell activation when inhibitory and activating receptors become co-engaged.

Host

Jurkat

Origin Species

Human

Target

Fc gamma RIIB / CD32b

Tag

Luc

Applications

• Determination of ADCP activity induced by antibodies.

Format

Liquid

Additionnal Information

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Shipping Conditions

Dry ice

Storage Conditions

Frozen in liquid nitrogen

Package Size

1Vial*2

Host or Source