Rituximab
Rituximab is an anti-CD20 chimeric monoclonal antibody used for research of certain autoimmune diseases and cancer.
Product Specifications
CAS Number
174722-31-7
Product Name Alternative
Anti-Human CD20 type I, Chimeric Antibody; HSDB 7455; IDEC-C2B8
UNSPSC
12352203
Hazard Statement
H372
Target
CD20; Radionuclide-Drug Conjugates (RDCs)
Type
Inhibitory Antibodies
Related Pathways
Antibody-drug Conjugate/ADC Related; Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/Rituximab.html
Purity
99.85
Solubility
H2O
Smiles
[Rituximab]
Molecular Weight
(143.47 kDa)
Precautions
P260-P264-P270-P501
References & Citations
[1]Kamburova EG, et al. In vitro effects of rituximab on the proliferation, activation and differentiation of human B cells. Am J Transplant. 2012 Feb;12 (2) :341-50.|[2]Manches O, et al. In vitro mechanisms of action of rituximab on primary non-Hodgkin lymphomas. Blood. 2003 Feb 1;101 (3) :949-54.|[3]Byrd JC, et al. The mechanism of tumor cell clearance by rituximab in vivo in patients with B-cell chronic lymphocytic leukemia: evidence of caspase activation and apoptosis induction. Blood. 2002 Feb 1;99 (3) :1038-43.
Shipping Conditions
Dry Ice
Storage Conditions
Store at -80°C for 2 years
Scientific Category
Inhibitory Antibodies
Clinical Information
Launched
Isoform
RDC Antibody
Available Sizes
Frequently Asked Questions
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