AChE-IN-67
Product Specifications
UNSPSC Description
AChE-IN-67 (compound 8n) is a potent AChE inhibitor, with an IC50 of 0.033 μM. AChE-IN-67 exhibits activity similar to Donepezil (HY-14566). AChE-IN-67 exhibits high blood-brain barrier (BBB) permeability. AChE-IN-67 can be used for Alzheimer's disease research[1].
Target Antigen
Cholinesterase (ChE)
Type
Reference compound
Related Pathways
Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ache-in-67.html
Smiles
O=C(N/N=C/C1=CC=CN1)CN(N(C)C(C2=C3C=CC=C2)=O)C3=O
Molecular Weight
325.32
References & Citations
[1]Nuha D, et al. Design, synthesis, biological evaluation, and molecular modeling simulations of new phthalazine-1,4-dione derivatives as anti-Alzheimer's agents. Arch Pharm (Weinheim). 2024 Jul 5:e2400067.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-161842/AChE-IN-67-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-161842/
Clinical Information
No Development Reported
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