Pomalidomide-amino-PEG4-NH2
Pomalidomide-amino-PEG4-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology[1].
Product Specifications
CAS Number
[2331259-44-8]
UNSPSC
12352005
Target
E3 Ligase Ligand-Linker Conjugates
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pomalidomide-amino-peg4-nh2.html
Solubility
10 mM in DMSO
Smiles
O=C(NC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O)COCCOCCOCCOCCN
Molecular Formula
C23H30N4O9
Molecular Weight
506.51
References & Citations
[1]Sato T, et al. Cereblon-Based Small-Molecule Compounds to Control Neural Stem Cell Proliferation in Regenerative Medicine. Front Cell Dev Biol. 2021;9:629326. Published 2021 Mar 11.|[2]Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27 (8) :998-985.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Cereblon
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS6472731-01 0.1 mL
DLK2, CT (Epidermal Growth Factor-like Protein 9, EGF-like Protein 9, Protein delta Homolog 2, DLK-2, EGFL9, UNQ2903/PRO28633) (MaxLight 550)
Sign In for Pricing
View Details 
MBS6472731-02 5x 0.1 mL
DLK2, CT (Epidermal Growth Factor-like Protein 9, EGF-like Protein 9, Protein delta Homolog 2, DLK-2, EGFL9, UNQ2903/PRO28633) (MaxLight 550)
Sign In for Pricing
View Details 
058373-01 10 µg
Leptin (LEP), Recombinant, Porcine, His-Tag, TRxA-Tag
Sign In for Pricing
View Details 058373-02 50 µg
Leptin (LEP), Recombinant, Porcine, His-Tag, TRxA-Tag
Sign In for Pricing
View Details 058373-03 100 µg
Leptin (LEP), Recombinant, Porcine, His-Tag, TRxA-Tag
Sign In for Pricing
View Details 058373-04 200 µg
Leptin (LEP), Recombinant, Porcine, His-Tag, TRxA-Tag
Sign In for Pricing
View Details