5 (6) -Carboxy-2',7'-dichlorofluorescein

5 (6) -Carboxy-2',7'-dichlorofluorescein is an ideal substrate for MRP2 vesicular transport assay, with excellent detection and transport properties[1].

Product Specifications

CAS Number

[111843-78-8]

UNSPSC

12171500

Hazard Statement

H315, H319, H335

Target

Fluorescent Dye; P-glycoprotein

Type

Dye Reagents

Related Pathways

Membrane Transporter/Ion Channel; Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/5-6-carboxy-2-7-dichlorofluorescein.html

Purity

99.03

Solubility

DMSO : 31.25 mg/mL (ultrasonic)

Smiles

OC(C1=CC=C(C2(OC3=O)C4=C(C=C(O)C(Cl)=C4)OC5=C2C=C(Cl)C(O)=C5)C3=C1)=O.O=C(C6=CC=C(C(O)=O)C=C67)OC87C9=C(C=C(O)C(Cl)=C9)OC%10=C8C=C(Cl)C(O)=C%10

Molecular Formula

C21H10Cl2O7

Molecular Weight

445.21

Precautions

H315, H319, H335

References & Citations

[1]Heredi-Szabo K, et al. Characterization of 5 (6) -carboxy-2, '7'-dichlorofluorescein transport by MRP2 and utilization of this substrate as a fluorescent surrogate for LTC4. J Biomol Screen. 2008 Apr;13 (4) :295-301.