SIIVFEKL (TFA)
SIIVFEKL TFA is a variant of the major MHC class I-restricted epitope SIINFEKL. SIIVFEKL TFA is an antigenic peptide, that can stimulate specific T cells in experimental settings to study the competitive interaction between T cells. SIIVFEKL TFA exhibits low affinity for the OT-I T cell receptor (TCR), and can be used for detection of CD8+ T cells[1].
Product Specifications
UNSPSC
12352209
Target
MHC
Type
Peptides
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/siivfekl-tfa.html
Purity
99.85
Solubility
H2O : ≥ 2 mg/mL
Smiles
CC(C)C[C@@H](C(O)=O)NC([C@H](CCCCN)NC([C@H](CCC(O)=O)NC([C@@H](NC([C@H](C(C)C)NC([C@H]([C@@H](C)CC)NC([C@H]([C@@H](C)CC)NC([C@@H](N)CO)=O)=O)=O)=O)CC1=CC=CC=C1)=O)=O)=O.O=C(C(F)(F)F)O.[x]
Molecular Formula
C46H77N9O12.xC2HF3O2
Molecular Weight
948.16 (free acid)
References & Citations
[1]Petkau G, et al., Zfp36l1 establishes the high-affinity CD8 T-cell response by directly linking TCR affinity to cytokine sensing. Eur J Immunol. 2024 Feb;54 (2) :e2350700.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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