BQU57
Product Specifications
UNSPSC Description
BQU57 selectively inhibits Ral, with higher selectivity than Ras or Rho. The IC50 values of BQU57 on H2122 and H358 cells are 2.0 μM and 1.3 μM respectively.
Target Antigen
Ras
Type
Reference compound
Related Pathways
GPCR/G Protein;MAPK/ERK Pathway
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/BQU57.html
Purity
99.45
Solubility
DMSO : ≥ 100 mg/mL
Smiles
NC1=C(C#N)C(C(C(C)=NN2C)=C2O1)C3=CC=C(C(F)(F)F)C=C3
Molecular Weight
334.30
References & Citations
[1]Yan C, et al. Discovery and characterization of small molecules that target the GTPase Ral. Nature. 2014 Nov 20;515(7527):443-447.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-12875/BQU57-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-12875/BQU57-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
1637739-82-2
Available Sizes
Curated Selection
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