Iclaprim-d6
Iclaprim-d6 (AR-100-d6) is the deuterium labeled Iclaprim. Iclaprim is a new selective bacterial Dihydrofolate inhibitor, which can inhibit the growth of S. aureus (MRSA) with an MIC90 of 0.06 μg/mL.
Product Specifications
CAS Number
1130072-57-9
UNSPSC
12352005
Target
Antibiotic; Bacterial; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Anti-infection; Others
Applications
COVID-19-immunoregulation
Field of Research
Infection
Solubility
10 mM in DMSO
Smiles
C(C1=C2C(=C(OC([2H])([2H])[2H])C(OC([2H])([2H])[2H])=C1)OC(C=C2)C3CC3)C=4C(N)=NC(N)=NC4
Molecular Formula
C19H16D6N4O3
Molecular Weight
360.44
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Schneider P, et al. Iclaprim, a novel diaminopyrimidine with potent activity on trimethoprim sensitive and resistant bacteria. Bioorg Med Chem Lett. 2003 Dec 1;13 (23) :4217-21.|[3]Kohlhoff SA, et al. Iclaprim. Expert Opin Investig Drugs. 2007 Sep;16 (9) :1441-8.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
bs-22217R-Cy5.5 100 µL
KRG2/DDX11 Polyclonal Antibody, Cy5.5 Conjugated
Sign In for Pricing
View Details 
bs-11815R-BF680-01 20 µL
CBLN2 Polyclonal Antibody, AbBy Fluor™ 680 Conjugated
Sign In for Pricing
View Details bs-11815R-BF680-02 100 µL
CBLN2 Polyclonal Antibody, AbBy Fluor™ 680 Conjugated
Sign In for Pricing
View Details CF500468 100 µg
ERK2 (MAPK1) Mouse Monoclonal Antibody [Clone ID: OTI6F8]
Sign In for Pricing
View Details 
32359061 1.0 µg DNA
NXF2B Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)
Sign In for Pricing
View Details 