Anatoxin-a

Product Specifications

CAS Number

64285-06-9

UNSPSC Description

Anatoxin-a (ATX-a) is a neurotoxic alkaloid. Anatoxin-a acts as both a nicotinic acetylcholine receptor (nAChR) agonist and an Acetylcholinesterase (AChE) inhibitor[1][2].

Target Antigen

Cholinesterase (ChE); nAChR

Type

Natural Products

Related Pathways

Membrane Transporter/Ion Channel;Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/anatoxin-a.html

Solubility

10 mM in DMSO

Smiles

[H][C@@]1(N2)CCC=C([C@@]2([H])CC1)C(C)=O

Molecular Weight

165.23

References & Citations

[1]Mir SA, et al. An exploration of the binding prediction of anatoxin-a and atropine to acetylcholinesterase enzyme using multi-level computer simulations. Phys Biol. 2023 Nov 23;21(1). |[2]Colas S, et al. Anatoxin-a: Overview on a harmful cyanobacterial neurotoxin from the environmental scale to the molecular target. Environ Res. 2021 Feb;193:110590.