Recombinant Human Granulocyte colony-stimulating factor protein (CSF3) (Active)
Product Specifications
Background
Granulocyte, macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. This CSF induces granulocytes.
Product Name Alternative
G-CSF, Filgrastim, Lenograstim
Gene ID
1440
UniProt
P09919
Target
TPLGPASSLP QSFLLKCLEQ VRKIQGDGAA LQEKLCATYK LCHPEELVLL GHSLGIPWAP LSSCPSQALQ LAGCLSQLHS GLFLYQGLLQ ALEGISPELG PTLDTLQLDV ADFATTIWQQ MEELGMAPAL QPTQGAMPAF ASAFQRRAGG VLVASHLQSF LEVSYRVLRH LAQP
Purification
>98% as determined by SDS-PAGE and HPLC.
Bioactivity
Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using murine NFS-60 cells is less than 0.1 ng, ml, corresponding to a specific activity of 1.0 107 IU, mg.
Storage Conditions
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Calculated Molecular Weight
18.7 kDa
Formulation
0.2 ?m filtered 10mM sodium acetate buffer, containing 5 % trehalose, pH 4.0 , lyophilized
Host or Source
E.Coli
Curated Selection
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