Zenarestat

Zenarestat is a potent and orally active aldose reductase inhibitor. Zenarestat improves diabetic peripheral neuropathy in Zucker diabetic fatty rats[1].

Product Specifications

CAS Number

[112733-06-9]

Product Name Alternative

AMD 3100; JM3100; SID791

UNSPSC

12352005

Target

Aldose Reductase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/zenarestat.html

Purity

99.35

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(CN1C(N(C(C2=C1C=C(C=C2)Cl)=O)CC3=CC=C(C=C3F)Br)=O)O

Molecular Formula

C17H11BrClFN2O4

Molecular Weight

441.64

References & Citations

[1]Shimoshige Y, et al. The effects of zenarestat, an aldose reductase inhibitor, on peripheral neuropathy in Zucker diabetic fatty rats. Metabolism. 2000;49 (11) :1395-1399.