Zenarestat
Zenarestat is a potent and orally active aldose reductase inhibitor. Zenarestat improves diabetic peripheral neuropathy in Zucker diabetic fatty rats[1].
Product Specifications
CAS Number
112733-06-9
Product Name Alternative
AMD 3100; JM3100; SID791
UNSPSC
12352005
Target
Aldose Reductase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/zenarestat.html
Purity
99.35
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(CN1C(N(C(C2=C1C=C(C=C2)Cl)=O)CC3=CC=C(C=C3F)Br)=O)O
Molecular Formula
C17H11BrClFN2O4
Molecular Weight
441.64
References & Citations
[1]Shimoshige Y, et al. The effects of zenarestat, an aldose reductase inhibitor, on peripheral neuropathy in Zucker diabetic fatty rats. Metabolism. 2000;49 (11) :1395-1399.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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