ElteN378
ElteN378 is an inhibitors of FKBP12e. ElteN378 can be used in study Alzheimer disease, Parkinson disease, Amyotrophic Lateral Sclerosis, proliferation disorders and cancer[1].
Product Specifications
CAS Number
1421366-99-5
UNSPSC
12352005
Target
FKBP
Type
Reference compound
Related Pathways
Apoptosis; Autophagy; Cell Cycle/DNA Damage; Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/elten378.html
Purity
99.96
Solubility
10 mM in DMSO
Smiles
O=C(N(CCCC1)[C@@H]1C(NCCCC2=CC=CC=C2)=O)C(C3=CC=CC=C3)=O
Molecular Formula
C23H26N2O3
Molecular Weight
378.46
References & Citations
[1]Martina MR, et al. The precise chemical-physical nature of the pharmacore in FK506 binding protein inhibition: ElteX, a New class of nanomolar FKBP12 ligands. J Med Chem. 2013 Feb 14;56 (3) :1041-51.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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