8-OH-DPAT (hydrobromide)
Product Specifications
UNSPSC Description
8-OH-DPAT (8-Hydroxy-DPAT) hydrobromide is a potent and selective 5-HT1A agonist with a pIC50 of 8.19. 8-OH-DPAT hydrobromide has selectivity of almost 1000 fold for a subtype of the 5-HT1 binding site[1].
Target Antigen
5-HT Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein;Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/8-oh-dpat-hydrobromide.html
Solubility
DMSO : 25 mg/mL (ultrasonic)
Smiles
OC1=C2CC(N(CCC)CCC)CCC2=CC=C1.[H]Br
Molecular Weight
328.29
References & Citations
[1]D N Middlemiss, et al. 8-Hydroxy-2-(di-n-propylamino)-tetralin discriminates between subtypes of the 5-HT<sub>1 </sub> recognition site. Eur J Pharmacol. 1983 May 20;90(1):151-3.|[2]Michael A Taffe, et al. Cognitive performance of MDMA-treated rhesus monkeys: sensitivity to serotonergic challenge. Neuropsychopharmacology. 2002 Dec;27(6):993-1005.Eur J Pharmacol. 2023 Oct 21:176147.|Nature. 2024 Jun;630(8015):237-246.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-15688/8-OH-DPAT-hydrobromide-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-15688/8-OH-DPAT-hydrobromide-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
76135-31-4
Available Sizes
Curated Selection
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