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Nicotinamide N-oxide

Product Specifications

UNSPSC Description

Nicotinamide N-oxide, an in vivo nicotinamide metabolite, is a potent, and selective antagonist of the CXCR2 receptor.

Target Antigen

CXCR; Drug Metabolite; Endogenous Metabolite; Oxidative Phosphorylation

Type

Natural Products

Related Pathways

GPCR/G Protein;Immunology/Inflammation;Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology; Endocrinology

Assay Protocol

https://www.medchemexpress.com/Nicotinamide_N-oxide.html

Purity

99.85

Solubility

DMSO : 10 mg/mL (ultrasonic)|H2O : 20 mg/mL (ultrasonic)

Smiles

O=C(C1=C[N+]([O-])=CC=C1)N

Molecular Weight

138.126

References & Citations

[1]Real AM, et al. Nicotinamide N-oxidation by CYP2E1 in human liver microsomes. Drug Metab Dispos. 2013 Mar;41(3):550-3.|[2]Cutshall NS, et al. Nicotinamide N-oxides as CXCR2 antagonists. Bioorg Med Chem Lett. 2001 Jul 23;11(14):1951-4.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-101407/Nicotinamide-N-oxide-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-101407/Nicotinamide-N-oxide-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

1986-81-8

Available Sizes

Curated Selection

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