8-Hydroxy loxapine

8-Hydroxy loxapine is the relatively inactive oxidative metabolite of Loxapine (HY-17390), compared to 7-OH-loxapine[1].

Product Specifications

CAS Number

[61443-77-4]

UNSPSC

12352005

Hazard Statement

H302+H312+H332-H315-H319

Target

Endogenous Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/8-hydroxy-loxapine.html

Smiles

ClC1=CC2=C(OC3=C(N=C2N4CCN(CC4)C)C=C(C=C3)O)C=C1

Molecular Formula

C18H18ClN3O2

Molecular Weight

343.81

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P501

References & Citations

[1]Zimmer JS, et al., Validation of HPLC-MS/MS methods for analysis of loxapine, amoxapine, 7-OH-loxapine, 8-OH-loxapine and loxapine N-oxide in human plasma. Bioanalysis. 2010 Dec;2 (12) :1989-2000.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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