VPC32183
VPC32183 is a competitive antagonist of LPA1 and LPA3 receptors. The activity of VPC32183 can inhibit lipid phosphatase 1 (LPP1), thereby preventing the activation of ERK (1/2) by dioctanoic acid diglyceride (DGPP 8:0) . By reducing the expression of LPP1, VPC32183 can further reduce DGPP 8:0-induced ERK (1/2) activation. The effects of VPC32183 suggest that it may have a positive regulatory function in cell signaling processes[1].
Product Specifications
CAS Number
717110-61-7
UNSPSC
12352005
Target
Endogenous Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/vpc32183.html
Smiles
CCCCCCCC/C=C\CCCCCCCC(N[C@H](COP(O)(O)=O)CC1=CC=C(C=C1)OCC2=CC=CC=N2)=O
Molecular Formula
C33H51N2O6P
Molecular Weight
602.74
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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