Clomiphene (citrate) (Standard)

Clomiphene (citrate) (Standard) is the analytical standard of Clomiphene (citrate) . This product is intended for research and analytical applications. Clomiphene citrate (Clomifene citrate) is an orally active estrogen-receptor modulator. Clomiphene citrate has anti-cancer actixity, induces perturbations during meiotic maturation and cytogenetic abnormalities and ameliorates in managing psychiatric and cognitive impairment[1][2][3].

Product Specifications

CAS Number

[50-41-9]

Product Name Alternative

Clomifene citrate (Standard)

UNSPSC

12352005

Hazard Statement

H361

Target

Estrogen Receptor/ERR; Reference Standards

Type

Reference Standards

Related Pathways

Others; Vitamin D Related/Nuclear Receptor

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Cancer; Endocrinology; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/clomiphene-citrate-standard.html

Purity

98.44

Smiles

Cl/C(C1=CC=CC=C1)=C(C2=CC=CC=C2)/C3=CC=C(OCCN(CC)CC)C=C3.OC(CC(O)=O)(C(O)=O)CC(O)=O

Molecular Formula

C32H36ClNO8

Molecular Weight

598.08

Precautions

H361

References & Citations

[1]Jiann B P, et al. Effect of clomiphene on Ca2+ movement in human prostate cancer cells [J]. Life Sciences, 2002, 70 (26) : 3167-3178.|[2]London S N, et al. Clomiphene citrate-induced perturbations during meiotic maturation and cytogenetic abnormalities in mouse oocytes in vivo and in vitro [J]. Fertility and sterility, 2000, 73 (3) : 620-626.|[3]Akintoye O O, et al. Synergistic action of carvedilol and clomiphene in mitigating the behavioral phenotypes of letrozole-model of PCOS rats by modulating the NRF2/NFKB pathway [J]. Life Sciences, 2023, 324: 121737.