Decanoic acid-d5

Decanoic acid-d5 is the deuterium labeled Decanoic acid. Decanoic acid, a component of medium chain triclycerides, is a brain-penetrant and non-competitive inhibitor of AMPA receptor. Decanoic acid has antiseizure effects[1][2][3].

Product Specifications

CAS Number

[1219803-00-5]

UNSPSC

12352211

Hazard Statement

H302-H315-H319-H335

Target

IGluR

Type

Isotope-Labeled Compounds

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Purity

98.30

Solubility

DMSO : 200 mg/mL (ultrasonic)

Smiles

[2H]C([2H])([2H])C([2H])([2H])CCCCCCCC(O)=O

Molecular Formula

C10H15D5O2

Molecular Weight

177.30

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Boison D, et, al. New insights into the mechanisms of the ketogenic diet. Curr Opin Neurol. 2017 Apr;30 (2) :187-192.|[3]Chang P, et al. Seizure control by decanoic acid through direct AMPA receptor inhibition. Brain. 2016 Feb;139 (Pt 2) :431-43.|[4]Kim S, et, al. Selective production of decanoic acid from iterative reversal of β-oxidation pathway. Biotechnol Bioeng. 2018 May;115 (5) :1311-1320.