VEGFR2/Flk-1/KDR Human

<strong>VEGFR2/Flk-1/KDR Human</strong>_x000D_ <strong>Catalog number:</strong> B2013722_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 20 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> 84.1 kDa_x000D_ <strong>Supplied as:</strong> Powder_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20¬∞C_x000D_ <strong>Keywords:</strong> CD309, VEGFR, kinase insert domain receptor_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MŒ©-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Zhou W, Liu K, Zeng L, He J, Gao X, Gu X, Chen X, Jing Li J, Wang M, Wu D, Cai Z, Claesson-Welsh L, Ju R, Wang J, Zhang F, Chen Y. Targeting VEGF-A/VEGFR2 Y949 Signaling-Mediated Vascular Permeability Alleviates Hypoxic Pulmonary Hypertension Circulation. 2022 Dec 13;146(24):1855-1881._x000D_ 2: Eguchi R, Kawabe JI, Wakabayashi I. VEGF-Independent Angiogenic Factors: Beyond VEGF/VEGFR2 Signaling J Vasc Res. 2022;59(2):78-89._x000D_ 3: Sun J, Huang W, Yang SF, Zhang XP, Yu Q, Zhang ZQ, Yao J, Li KR, Jiang Q, Cao C. Gi1 and Gi3mediate VEGF-induced VEGFR2 endocytosis, signaling and angiogenesis Theranostics. 2018 Sep 9;8(17):4695-4709._x000D_ 4: Zhou HJ, Xu Z, Wang Z, Zhang H, Zhuang ZW, Simons M, Min W. SUMOylation of VEGFR2 regulates its intracellular trafficking and pathological angiogenesis Nat Commun. 2018 Aug 17;9(1):3303._x000D_ 5: Liu K, Ren T, Huang Y, Sun K, Bao X, Wang S, Zheng B, Guo W. Apatinib promotes autophagy and apoptosis through VEGFR2/STAT3/BCL-2 signaling in osteosarcoma Cell Death Dis. 2017 Aug 24;8(8):e3015._x000D_ 6: Zhong M, Li N, Qiu X, Ye Y, Chen H, Hua J, Yin P, Zhuang G. TIPE regulates VEGFR2 expression and promotes angiogenesis in colorectal cancer Int J Biol Sci. 2020 Jan 1;16(2):272-283._x000D_ 7: Mateluna C, Torres P, Rodriguez-Pea M, Silva P, Matthies DJ, Criollo A, Bikker FJ, Bolscher JGM, Wilson CAM, Zapata-Torres G, Torres VA. Identification of VEGFR2 as the Histatin-1 receptor in endothelial cells Biochem Pharmacol. 2022 Jul;201:115079._x000D_ 8: Zhu P, Hu C, Hui K, Jiang X. The role and significance of VEGFR2(+) regulatory T cells in tumor immunity Onco Targets Ther. 2017 Sep 1;10:4315-4319._x000D_ 9: Prasad CB, Singh D, Pandey LK, Pradhan S, Singh S, Narayan G. VEGFa/VEGFR2 autocrine and paracrine signaling promotes cervical carcinogenesis via _-catenin and snail Int J Biochem Cell Biol. 2022 Jan;142:106122._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/36928770">10: Cho HD, Nhn NTT, Zhou C, Tu K, Nguyen T, Sarich NA, Yamada KH. KIF13B mediates VEGFR2 recycling to modulate vascular permeability Cell Mol Life Sci. 2023 Mar 16;80(4):91. </a>_x000D_ _x000D_ <strong>Products Related to VEGFR2/Flk-1/KDR Human can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>