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Beta-defensin 1 Rabbit pAb

Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 1, an antimicrobial peptide implicated in the resistance of epithelial surfaces to microbial colonization. This gene maps in close proximity to defensin family member, defensin, alpha 1 and has been implicated in the pathogenesis of cystic fibrosis. [provided by RefSeq, Jul 2008],

Product Specifications

Background

Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 1, an antimicrobial peptide implicated in the resistance of epithelial surfaces to microbial colonization. This gene maps in close proximity to defensin family member, defensin, alpha 1 and has been implicated in the pathogenesis of cystic fibrosis. [provided by RefSeq, Jul 2008]

Product Name Alternative

Beta-defensin 1 (BD-1; hBD-1; Defensin, beta 1)

UniProt

P60022

Swiss Prot

P60022

Reactivity

Human; Rat; Mouse

Immunogen

Synthesized peptide derived from human Beta-defensin 1 AA range: 1-50

Target

Beta-defensin 1

Clonality

Polyclonal

Source

Rabbit

Applications

IHC; ELISA

Concentration

1 mg/ml

Dilution

IHC-p 1:50-200, ELISA (peptide) 1:5000-20000

Buffer

-20°C/1 year

Storage Conditions

-20°C/1 year

Fragment

IgG

Subcellular Location

Secreted . Membrane . Associates with tumor cell membrane-derived microvesicles (PubMed:23938203) . .

Other Product Names

Beta-defensin 1 (BD-1; hBD-1; Defensin, beta 1)

Gene ID (Human)

1672

Available Sizes

Curated Selection

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