TXNIP-IN-1
TXNIP-IN-1 is TXNIP-TRX (thioredoxin-interacting protein- thioredoxin) complex inhibitor extracted from patent US20200085800A1, Compound 1. TXNIP-IN-1 can be used in the research of TXNIP-TRX complex associated metabolic disorder (diabetes), cardiovascular disease, or inflammatory disease[1].
Product Specifications
CAS Number
[1268955-50-5]
Product Name Alternative
DDD00107587,EPZ015866; GSK3203591,EPZ015866 (hydrochloride); GSK3203591 (hydrochloride)
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
Arrestin
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease; Inflammation/Immunology; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/txnip-in-1.html
Concentration
10mM
Purity
98.90
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(O)C(C(C)C)N(C1=O)C(C2=C1C=CN=C2)=O
Molecular Formula
C12H12N2O4
Molecular Weight
248.24
Precautions
H315, H319, H335
References & Citations
[1]Rama Natarajan, et al. Txnip-trx complex inhibitors and methods of using the same. US20200085800A1.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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