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SNIPER(TACC3)-11

Product Specifications

UNSPSC Description

SNIPER(TACC3)-11 is a potent FGFR3-TACC3 degrader. SNIPER(TACC3)-11 reduces FGFR3-TACC3 protein levels and suppressed the growth of FGFR3-TACC3 positive cancer cells[1].

Target Antigen

FGFR; SNIPERs

Type

Reference compound

Related Pathways

PROTAC;Protein Tyrosine Kinase/RTK

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/sniper-tacc3-11.html

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CN[C@H](C(N[C@@H](C1CCCCC1)C(N2CCC[C@H]2C3=NC(C(C4=CC(OCCOCCOCCNC(C5=CC=C(C=C5)C6=NC(CNC7=NC=CC(NCC(C)C)=N7)=CS6)=O)=CC=C4)=O)=CS3)=O)=O)C

Molecular Weight

995.26

References & Citations

[1]Shibata N, Cho N, Koyama H, Naito M. Development of a degrader against oncogenic fusion protein FGFR3-TACC3. Bioorg Med Chem Lett. 2022;60:128584.

Shipping Conditions

Room Temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-145895/SNIPER-TACC3-11-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-145895/SNIPER-TACC3-11-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

2906151-68-4

Available Sizes

Curated Selection

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