SNIPER (TACC3) -11

[2906151-68-4]

12352005

FGFR; SNIPERs

Reference compound

PROTAC; Protein Tyrosine Kinase/RTK

Cancer-Kinase/protease

Cancer

https://www.medchemexpress.com/sniper-tacc3-11.html

99.58

DMSO : 100 mg/mL (ultrasonic)

CN[C@H](C(N[C@@H](C1CCCCC1)C(N2CCC[C@H]2C3=NC(C(C4=CC(OCCOCCOCCNC(C5=CC=C(C=C5)C6=NC(CNC7=NC=CC(NCC(C)C)=N7)=CS6)=O)=CC=C4)=O)=CS3)=O)=O)C

C51H66N10O7S2

995.26

[1]Shibata N, Cho N, Koyama H, Naito M. Development of a degrader against oncogenic fusion protein FGFR3-TACC3. Bioorg Med Chem Lett. 2022;60:128584.

Room Temperature

-20°C, 3 years; 4°C, 2 years (Powder)

Reference compound1

No Development Reported