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Glutaminyl cyclases-IN-2

Glutaminyl cyclases-IN-2 (compound 27) is a potent inhibitor of glutaminyl cyclase, with the IC50 of 0.08 μM. Glutaminyl cyclases-IN-2 plays an important role in cancer research[1].

Product Specifications

UNSPSC

12352005

Target

Amyloid-β

Type

Reference compound

Related Pathways

Neuronal Signaling

Field of Research

Cancer; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/glutaminyl-cyclases-in-2.html

Smiles

CC1=CN=CN1CCCNC2=CC=CC=C2C3=CC(OC)=C(OC)C(OC)=C3

Molecular Formula

C22H27N3O3

Molecular Weight

381.47

References & Citations

[1]Qingqing Zhou, et al. Design, synthesis, and evaluation of 4- (4-methyl-4H-1,2,4-triazol-3-yl) piperidine derivatives as potential glutaminyl cyclase isoenzyme inhibitors for the treatment of cancer. Eur J Med Chem. 2024 Nov 1:281:117019.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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