Glutaminyl cyclases-IN-2
Glutaminyl cyclases-IN-2 (compound 27) is a potent inhibitor of glutaminyl cyclase, with the IC50 of 0.08 μM. Glutaminyl cyclases-IN-2 plays an important role in cancer research[1].
Product Specifications
UNSPSC
12352005
Target
Amyloid-β
Type
Reference compound
Related Pathways
Neuronal Signaling
Field of Research
Cancer; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/glutaminyl-cyclases-in-2.html
Smiles
CC1=CN=CN1CCCNC2=CC=CC=C2C3=CC(OC)=C(OC)C(OC)=C3
Molecular Formula
C22H27N3O3
Molecular Weight
381.47
References & Citations
[1]Qingqing Zhou, et al. Design, synthesis, and evaluation of 4- (4-methyl-4H-1,2,4-triazol-3-yl) piperidine derivatives as potential glutaminyl cyclase isoenzyme inhibitors for the treatment of cancer. Eur J Med Chem. 2024 Nov 1:281:117019.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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