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SR 142948A

Product Specifications

UNSPSC Description

SR 142948A is a non-peptide neuropeptide neuropeptin (NT) receptor antagonist. SR 142948A is able to bind to neuropeptin receptors, especially with high affinity for NT1 and NT2 receptors. SR 142948A is mainly used to study the role of neuropeptide in the neurotransmitter system, especially the dopamine system[1].

Target Antigen

Others

Type

Reference compound

Related Pathways

Others

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/sr-142948a.html

Purity

98.90

Solubility

H2O : 10 mg/mL (ultrasonic;warming)

Smiles

O=C(C1(NC(C2=NN(C3=CC=C(C(N(CCCN(C)C)C)=O)C=C3C(C)C)C(C4=C(OC)C=CC=C4OC)=C2)=O)C5CC6CC(C5)CC1C6)O.Cl

Molecular Weight

722.31

References & Citations

[1]Leonetti M, et al. The neurotensin receptor antagonist SR 142948A blocks the efflux of dopamine evoked in nucleus accumbens by neurotensin ejection into the ventral tegmental area[J]. Naunyn-Schmiedeberg's Archives of Pharmacology, 2002, 365: 427-433.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-124767/SR-142948A-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-124767/SR-142948A-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

184162-21-8

Available Sizes

Curated Selection

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