SR 142948A
Product Specifications
UNSPSC Description
SR 142948A is a non-peptide neuropeptide neuropeptin (NT) receptor antagonist. SR 142948A is able to bind to neuropeptin receptors, especially with high affinity for NT1 and NT2 receptors. SR 142948A is mainly used to study the role of neuropeptide in the neurotransmitter system, especially the dopamine system[1].
Target Antigen
Others
Type
Reference compound
Related Pathways
Others
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/sr-142948a.html
Purity
98.90
Solubility
H2O : 10 mg/mL (ultrasonic;warming)
Smiles
O=C(C1(NC(C2=NN(C3=CC=C(C(N(CCCN(C)C)C)=O)C=C3C(C)C)C(C4=C(OC)C=CC=C4OC)=C2)=O)C5CC6CC(C5)CC1C6)O.Cl
Molecular Weight
722.31
References & Citations
[1]Leonetti M, et al. The neurotensin receptor antagonist SR 142948A blocks the efflux of dopamine evoked in nucleus accumbens by neurotensin ejection into the ventral tegmental area[J]. Naunyn-Schmiedeberg's Archives of Pharmacology, 2002, 365: 427-433.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-124767/SR-142948A-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-124767/SR-142948A-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
184162-21-8
Available Sizes
Curated Selection
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