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AAV-8 NSL epitope

The AAV-8 NSL epitope is a specific CD8+ T cell epitope identified from the capsid of an adeno-associated virus (AAV) serotype 8. The AAV-8 NSL epitope has a high affinity for MHC I molecules and is able to bind to MHC I molecules, thereby activating CD8+ T cells. The AAV-8 NSL epitope can be used to study the impact of T cell-mediated immune responses on AAV-mediated gene transfer[1].

Product Specifications

CAS Number

872141-81-6

UNSPSC

12352209

Target

Others

Type

Peptides

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/aav-8-nsl-epitope.html

Smiles

O=C(N[C@@H](CO)C(N[C@@H](CC(C)C)C(N[C@@H](C)C(N[C@@H](CC(N)=O)C(N1[C@@H](CCC1)C(NCC(N[C@@H]([C@@H](C)CC)C(N[C@@H](C)C(O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CC(N)=O)N

Molecular Formula

C36H61N11O13

Molecular Weight

855.94

References & Citations

[1]Sabatino D E, et al. Identification of mouse AAV capsid-specific CD8+ T cell epitopes[J]. Molecular Therapy, 2005, 12 (6) : 1023-1033.

Shipping Conditions

Room temperature

Scientific Category

Peptides

Clinical Information

No Development Reported

Frequently Asked Questions

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