BM567
BM567 is a sulfonylurea compound (compound 1), which exhibits antithrombogenic efficacy as thromboxane A2 receptor (TXR) antagonists and thromboxane A2 synthase (TXS) inhibitors, with IC50s of 1.1 and 12 nM, respectively[1].
Product Specifications
CAS Number
284464-77-3
UNSPSC
12352005
Target
Prostaglandin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/bm567.html
Solubility
10 mM in DMSO
Smiles
O=S(C1=CC([N+]([O-])=O)=CC=C1NC2CCCCC2)(NC(NCCCCC)=O)=O
Molecular Formula
C18H28N4O5S
Molecular Weight
412.50
References & Citations
[1]Michaux C, et al., Structure determination and comparison of BM567, a sulfonylurea, with terbogrel, two compounds with dual action, thromboxane receptor antagonism and thromboxane synthase inhibition. Bioorg Med Chem Lett. 2001 Apr 23;11 (8) :1019-22.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
TXA2/TP
Available Sizes
Frequently Asked Questions
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