Piperazine Erastin

Piperazine erastin is an analog of erastin which induces an iron-dependent form of non-apoptotic cell death, termed ferroptosis. Piperazine erastin can be used in cancer research[1].

Product Specifications

CAS Number

[1538593-71-3]

UNSPSC

12352005

Hazard Statement

H302

Target

Ferroptosis

Type

Reference compound

Related Pathways

Apoptosis

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/Piperazine-Erastin.html

Purity

99.12

Solubility

DMSO : 33.33 mg/mL (ultrasonic)

Smiles

O=C1N(C2=CC(CN3CCNCC3)=CC=C2OC(C)C)C(CN4CCN(C(COC5=CC=C(Cl)C=C5)=O)CC4)=NC6=C1C=CC=C6

Molecular Formula

C35H41ClN6O4

Molecular Weight

645.19

Precautions

H302

References & Citations

[1]Yang WS, et al. Regulation of ferroptotic cancer cell death by GPX4. Cell. 2014 Jan 16;156 (1-2) :317-331.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

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