Piperazine Erastin
Piperazine erastin is an analog of erastin which induces an iron-dependent form of non-apoptotic cell death, termed ferroptosis. Piperazine erastin can be used in cancer research[1].
Product Specifications
CAS Number
[1538593-71-3]
UNSPSC
12352005
Hazard Statement
H302
Target
Ferroptosis
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/Piperazine-Erastin.html
Purity
99.12
Solubility
DMSO : 33.33 mg/mL (ultrasonic)
Smiles
O=C1N(C2=CC(CN3CCNCC3)=CC=C2OC(C)C)C(CN4CCN(C(COC5=CC=C(Cl)C=C5)=O)CC4)=NC6=C1C=CC=C6
Molecular Formula
C35H41ClN6O4
Molecular Weight
645.19
Precautions
H302
References & Citations
[1]Yang WS, et al. Regulation of ferroptotic cancer cell death by GPX4. Cell. 2014 Jan 16;156 (1-2) :317-331.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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