3-Nitrophenyl disulfide
3-Nitrophenyl disulfide (Bis (3-Nitrophenyl) disulfide) is an inhibitor of mannitol-1-phosphate dehydrogenase (M1PDH) with IC50 of 3 μM. 3-Nitrophenyl disulfide has antiparasitic activity[1].
Product Specifications
CAS Number
537-91-7
Product Name Alternative
Bis (3-nitrophenyl) disulfide; Nitrophenide
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335, H410
Target
Parasite
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/3-nitrophenyl-disulfide.html
Purity
99.27
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=[N+](C1=CC(SSC2=CC=CC([N+]([O-])=O)=C2)=CC=C1)[O-]
Molecular Formula
C12H8N2O4S2
Molecular Weight
308.33
Precautions
H302, H315, H319, H335, H410
References & Citations
[1]Allocco JJ, et al. Nitrophenide (Megasul) blocks Eimeria tenella development by inhibiting the mannitol cycle enzyme mannitol-1-phosphate dehydrogenase. J Parasitol. 2001 Dec;87 (6) :1441-8.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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