MMH1-NR
MMH1-NR, containing a non-reactive (ethyl) group is a negative control of MMH1. MMH1 is a CUL4-associated factor (DCAF16) -based bromodomain protein 4 (BRD4) degrader[1].
Product Specifications
UNSPSC
12352005
Target
Epigenetic Reader Domain; Molecular Glues
Type
Reference compound
Related Pathways
Epigenetics; PROTAC
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mmh1-nr.html
Purity
99.36
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC1=C(C)SC2=C1C(C3=CC=C(NC(CC)=O)C=C3)=N[C@@H](CC(OC(C)(C)C)=O)C4=NN=C(C)N42
Molecular Formula
C26H31N5O3S
Molecular Weight
493.62
References & Citations
[1]Yen-Der Li, et al. Template-assisted covalent modification of DCAF16 underlies activity of BRD4 molecular glue degraders. bioRxiv. 2023 Feb 15:2023.02.14.528208.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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