MMH1-NR

MMH1-NR, containing a non-reactive (ethyl) group is a negative control of MMH1. MMH1 is a CUL4-associated factor (DCAF16) -based bromodomain protein 4 (BRD4) degrader[1].

Product Specifications

UNSPSC

12352005

Target

Epigenetic Reader Domain; Molecular Glues

Type

Reference compound

Related Pathways

Epigenetics; PROTAC

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/mmh1-nr.html

Purity

99.36

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CC1=C(C)SC2=C1C(C3=CC=C(NC(CC)=O)C=C3)=N[C@@H](CC(OC(C)(C)C)=O)C4=NN=C(C)N42

Molecular Formula

C26H31N5O3S

Molecular Weight

493.62

References & Citations

[1]Yen-Der Li, et al. Template-assisted covalent modification of DCAF16 underlies activity of BRD4 molecular glue degraders. bioRxiv. 2023 Feb 15:2023.02.14.528208.