ML354
ML354 is a selective PAR4 antagonist with an IC50 of 140 nM[1].
Product Specifications
CAS Number
[89159-60-4]
Product Name Alternative
VU0099704
UNSPSC
12352005
Hazard Statement
H301
Target
Protease Activated Receptor (PAR)
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/ml354.html
Purity
98.80
Solubility
DMSO : 28.2 mg/mL (ultrasonic; warming)
Smiles
OCC(N1C)=C(C2=CC=CC=C2)C3=C1C=CC([N+]([O-])=O)=C3
Molecular Formula
C16H14N2O3
Molecular Weight
282.29
Precautions
H301
References & Citations
[1]Wen W, et al. Substituted indoles as selective protease activated receptor 4 (PAR-4) antagonists: Discovery and SAR of ML354. Bioorg Med Chem Lett. 2014 Oct 1;24 (19) :4708-4713.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PAR4
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
ELK6055-01 48 Tests
Mouse ARPC4 (Actin Related Protein 2/3 Complex Subunit 4) ELISA Kit
Ask
View Details 
ELK6055-02 96 Tests
Mouse ARPC4 (Actin Related Protein 2/3 Complex Subunit 4) ELISA Kit
Ask
View Details ELK6055-03 5x 96 Tests
Mouse ARPC4 (Actin Related Protein 2/3 Complex Subunit 4) ELISA Kit
Ask
View Details 