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Decanedioic acid

Decanedioic acid is a straight-chain dicarboxylic acid. Dodecanedioic acid overcomes metabolic inflexibility in type 2 diabetes. Decanedioic acid prevents and reverses metabolic-associated liver disease and obesity. Decanedioic acid is associated with carnitine-acylcarnitine translocase deficiency and medium chain acyl-CoA dehydrogenase deficiency[1][2][3].

Product Specifications

CAS Number

111-20-6

Product Name Alternative

Sebacic acid

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

Endogenous Metabolite

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/Decanedioic_acid.html

Purity

99.96

Solubility

DMSO : ≥ 100 mg/mL|H2O : 1 mg/mL (ultrasonic; warming; heat to 80°C)

Smiles

O=C(O)CCCCCCCCC(O)=O

Molecular Formula

C10H18O4

Molecular Weight

202.25

Precautions

H302, H315, H319, H335

References & Citations

[1]Bertuzzi A, et al. Sebacic acid binding to human plasma albumin. Biochem Pharmacol. 1993 Feb 9;45 (3) :697-702.|[2]Angelini G, et al. Dodecanedioic acid prevents and reverses metabolic-associated liver disease and obesity and ameliorates liver fibrosis in a rodent model of diet-induced obesity. FASEB J. 2024 Nov 30;38 (22) :e70202.|[3]Salinari S, et al. Dodecanedioic acid overcomes metabolic inflexibility in type 2 diabetic subjects. American Journal of Physiology-Endocrinology and Metabolism, 2006, 291 (5) : E1051-E1058.

Shipping Conditions

Room Temperature

Storage Conditions

Store at room temperature 3 years

Scientific Category

Natural Products

Clinical Information

No Development Reported

Isoform

Human Endogenous Metabolite

Available Sizes

Frequently Asked Questions

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