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Trans-BAY-850

Trans-BAY-850 is the trans isomer of BAY-850. BAY-850 is a potent and isoform selective ATPase family AAA domain-containing protein 2 (ATAD2) inhibitor, with an IC50 of 166 nM.

Product Specifications

UNSPSC

12352005

Target

Epigenetic Reader Domain

Type

Reference compound

Related Pathways

Epigenetics

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/trans-bay-850.html

Purity

98.12

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(N[C@H](CC1=CC=C(C#N)C=C1)CN[C@@H]2CC[C@@H](N)CC2)C3=CC(C4=CC=C(CN[C@@H](C5=CC=C(C)C=C5)C)O4)=C(OC)C=C3Cl

Molecular Formula

C38H44ClN5O3

Molecular Weight

654.24

References & Citations

[1]Fernández-Montalván AE, et al. Isoform-Selective ATAD2 Chemical Probe with Novel Chemical Structure and Unusual Mode of Action. ACS Chem Biol. 2017 Nov 17;12 (11) :2730-2736.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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